By Dr. José Aldair Morsch, February 7, 2023 Patients – 24h on call. Prescription renewal, Teleconsultation Doctors – Sign up to see our patients subcutaneous route audio player. Use the up or down arrows to increase or decrease the volume. Insulin , : “The extensive network of capillaries enables the gradual absorption of the drug and guarantees the pharmacokinetic profile”. Another benefit is the relative ease of application , which allows subcutaneous injection of substances by caregivers or even patients. This possibility simplifies the use of medications such as insulin, which needs to be administered frequently in diabetic people. Finally, the subcutaneous route also serves as an alternative for patients with difficult access to the intravenous route , such as the elderly and babies. In these cases, there is also usually difficulty medicating the patient orally, which reinforces the importance of the SC route for various treatments. Among the disadvantages.

It is worth mentioning

The need for training and care to carry out this invasive procedure safely. After all, it is necessary to perform asepsis and use sterile materials to avoid contamination , as well as to perform firm movements to  reduce pain during the application of drugs. There is also a risk of tissue sensitization and lipodystrophy . What are the subcutaneous application sites? The New Zealand Phone Numbers List rotation between the application sites is fundamental for an effective absorption of the drug, in addition to avoiding the sensitization of the areas. The most common regions for subcutaneous application are: Upper outer arm areas abdomen front of thighs Upper back region. Also be aware of medications that should not be administered subcutaneously, as explained below. Which drugs are incompatible with the subcutaneous route? There are incompatible drugs, such as those mentioned in this study on the subcutaneous route for palliative.

According to the authors diazepam

Phenytoin and chlorpromazine should not be administered SC, due to the risk of tissue necrosis. Diclofenac and undiluted electrolytes are also contraindicated . How to administer drugs subcutaneously? Start by Executive List checking that the drug is diluted in water – a necessary step for most subcutaneously injected drugs . There are exceptions for ketamine, octreotide and ondansetron, which must be diluted in 0.9% saline. See an example described in the aforementioned manual of the Ministry of Health for administering drugs via SC: Check the necessary materials , such as solution prepared to be installed, equipment with doser (ml/hour), antiseptic solution, gauze, procedure glove, scalps 25, 27, 23 (butterfly type), syringes, transparent film to fix. Afterwards, proceed to the installation of the hypodermoclysis : Explain to the patient about the procedure Choose the infusion site Perform antisepsis and skin folding Insert the scalp at an angle.